Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how ...

Tech advances already show a future of testing in which we might not have to suffer and die while waiting for systems that ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

A perspective in the Journal of the Royal Society Interface argues that advances in AI, sensing technologies and modeling are ...

In this free webinar, learn how modeling and simulation can help navigate the Animal Rule in drug development. Attendees will gain insight into when the Animal Rule is appropriate to use for drug ...

Expert Rev Clin Pharmacol. 2012;5(6):667-676. Endophenotypes are defined as measurable intermediate disease features that bridge the gap between overt manifestations of schizophrenia and underlying ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.