Coined by 2022 Nobel laureate Carolyn Bertozzi, bioorthogonal chemistry encompasses a class of click reactions that are both fast and biologically inert, making them particularly useful in precision ...
Bioorthogonal chemistry has emerged as an influential field that bridges chemical innovation with biological application by enabling reactions that occur in living systems without interfering with ...
image: Through reviewing the typical and newly developed click reactions, researchers have tried to decipher the development logic behind this field. As the application range extends constantly, the ...
Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...
Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless have been awarded the 2022 Nobel Prize in Chemistry for their development of click chemistry and bioorthogonal chemistry, an ingenious tool ...
It has been almost a quarter-century since K. Barry Sharpless, M.G. Finn, and Hartmuth C. Kolb published the paper that some refer to as the click manifesto. In it, the researchers presented a vision ...
Heyang (Peter) Zhang works in Lin's lab at the University at Buffalo. The 2022 Nobel Prize in chemistry was awarded to scientists Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for their ...
The 2022 Nobel prize for Chemistry has been awarded to a trio for developing click chemistry, an environmentally friendly method for rapidly joining molecules to develop cancer treatments, create ...