Researchers analyzed DNA methylation in human skeletal muscle and identified age-linked epigenetic markers that enable highly ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Researchers analyzed gene expression and network connectivity across eight human tissues and found shared aging-related ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Switches' in our DNA that affect gene activity in cells could be crucial to understanding and possibly treating Alzheimer's ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.