One of the first intracellular kinases to be explicated as a protooncogene was c-Src, an upstream mediator of both the PI 3-K and MAPK pathways. The amplified c-Src activity has been implicated in ...

Host species have evolved mechanisms that can inhibit pathogen replication even after a cell has been successfully invaded. Here we show that tripartite-motif protein 21 (TRIM21), a ubiquitously ...

Announcing a new article publication for Zoonoses journal. Researchers from University of Texas Medical Branch, Galveston, TX, USA review pattern recognition receptors in innate immunity to obligate ...

This is a preview. Log in through your library . Abstract In the companion paper we have shown that pulse labeling of hepatic proteins with [35 S]cysteine can be obtained in vivo in intact rats.

Signal transduction is the term for the process which causes chemical and physical signals to be transmitted within a cell as a series of molecular events. The most common signal transduction process ...