Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...

Mitochondria are essential organelles that drive energy production, regulate apoptosis and orchestrate metabolic signalling within cells. Their dynamic nature underpins processes as diverse as ATP ...

Dr. Taz Bhatia M.D., a nationally recognized integrative medicine physician, author, and founder of hol+, has partnered with nonprofit Countdown for a Cure (CFAC) to help advance awareness, education, ...

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

Pretzel Therapeutics is advancing its mitochondrial disease therapies, pushing lead candidate PX578 through Phase 1 trials ...

While Alzheimer's Disease is traditionally associated with the buildup of plaques, emerging evidence suggests that mitochondrial dysfunction may play a role in the onset and progression of this ...

In recent years, there has been increasing evidence that mitochondrial dysfunction plays a causative role in Crohn's disease and other gastrointestinal disorders. This can happen for a variety of ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.