Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of ...

A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the ...

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...

In a recent study under review in the Journal of Hematology & Oncology journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

The investigators also studied laboratory mice with Kawasaki-like inflamed blood vessels and noted increased platelet counts. In addition, they observed the formation of monocyte-platelet aggregates ...

Neonatal alloimmune thrombocytopenia (NAIT) is a disorder that affects pregnant people and their fetuses. It occurs when the birthing parent’s immune system produces antibodies that attack and destroy ...

A 34-year-old woman (gravida 3, para 2) at 16 weeks’ gestation was found to have platelets unable to be quantified because of clumping on routine prenatal blood work, with a visual estimate of 40 ...

They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This decisive process is regulated by the innate immune system ...