Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...

Glaucoma is about many things, but most relate to a tiny piece of tissue called the trabecular meshwork, the exit filter for aqueous humor leaving the eye. A healthy trabecular meshwork (TM) permits ...

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, identifying a cell subtype that shows early signs of dysfunction in a genetic mouse model of glaucoma. Their study, ...

Schematic diagram illustrating possible mechanisms of APOE in trabecular meshwork degeneration with aging. The study delves into the age-related changes in the trabecular meshwork (TM) of macaques, ...