How to prevent blisters when running? Blisters are a common problem for runners, especially when they are starting out or increasing their mileage. Here are some tips to help prevent blisters when running: 1. Wear properly fitting shoes: Make sure your shoes fit well and are the right size for your feet. Avoid shoes that are too tight or too loose. I like an extra finger space between my toes and the shoes. Consider getting fitted professionally 2. Wear moisture-wicking socks: Choose socks that